View Article |
Real-time simulation of cardiac excitation using hardware-implemented cardiac excitation modeling
Farhanahani Mahmud1.
In this paper a hardware-implemented cardiac excitation model of a cardiac cell based on Luo-Rudy phase I (LR1) for the action potential (AP) generation in a mammalian cardiac ventricle is proposed to speed up the computational time during the simulation of the cardiac AP conduction. The hardware-implemented cardiac excitation model is designed by using analog circuits and a dsPIC microcontroller that could reproduce time dependent and time-independent nonlinear current-voltage characteristics of six-type of ionic currents in LR1 model. Through the study, real-time simulations of reentrant excitation conduction of cardiac cells are realized by coupling 30 active circuits of the cell models based on a cable model. The real-time simulations of initiation have been performed by the model and they are comparable to those from the LR1 model. Thus, it is conceivable that the hardware-implemented cardiac excitation model may be useful as one of alternative tools toward further understanding of the reentrant mechanisms.
Affiliation:
- Universiti Tun Hussein Onn Malaysia, Malaysia
|
|
Indexation |
Indexed by |
MyJurnal (2019) |
H-Index
|
0 |
Immediacy Index
|
0.000 |
Rank |
0 |
|
|
|