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The role of worm infestation in allergic rhinitis
Manuel, A.M1, Kuljit, S2, Gopalakrishnan, G3, Suresh, K.G4, Balraj, P5.
The purpose of this study is to determine the relevance of the hygiene hypothesis; that is to determine if worm infestation has a protective role against the development of allergic rhinitis. A prospective case controlled study was conducted. Specific IgG levels to Toxocara were studied in 85 patients confirmed to have allergic rhinitis and were compared to levels in another 85 controls, with no form of allergy. The IgG assay was done using ELISA technique. There was a higher incidence of positive specific IgG to Toxocara in the controls
as compared to allergic patients. The values were statistically significant [Chi square test
(p=0.002)]. This negative association between worm infestation and allergic rhinitis suggests
that a previous worm infestation could protect against the development of allergic rhinitis.
Affiliation:
- University of Malaya, Malaysia
- Prince Court Medical Centre, Malaysia
- University of Malaya, Malaysia
- University of Malaya, Malaysia
- Institute for Medical Research, Malaysia
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Indexation |
Indexed by |
MyJurnal (2019) |
H-Index
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0 |
Immediacy Index
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0.000 |
Rank |
0 |
Indexed by |
Web of Science (JCR 2016) |
Impact Factor
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0.719 |
Rank |
Q4 (Parasitology) Q4 (Tropical Medicine) |
Indexed by |
Scopus (SCImago Journal Rankings 2016) |
Impact Factor
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- |
Rank |
Q3 (Infectious Diseases) Q3 (Parasitology) |
Additional Information |
0.403 (SJR) |
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