This paper reviews production of some metabolites by a soil fungus Botryodiplodia theobromae, including enzymes, hormones, exopolysaccharides, and paclitaxel/taxol, for therapeutic use, and for food industry.Paclitaxel, an anti-cancer agent, is produced when the fungus grows as an endophytic fungus. B. theobromae produces linear and branchedexoplysaccharide β-glucan, called lasiodiplodin, which shows various therapeutic activities: anti-tumor, hypoglycemic, anti-coagulant, anti-cancer, while protecting against DNA damage. Lasiodiplodins also show cytotoxicity against murine leukemia cell line. The fungus is known to produce amylase and glucoamylase to degrade starch into sugar for various process in food industry.