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Efficacy of anti-tuberculosis treatment alone on resolution of tuberculosis pleural effusions
Selvarajah, V.S1, Samudram, S2, Chua, L.T3, Yuhana, D. Siti4, Lim, B.K5, S. Wan Yusuf6, Loh, L. C7.
To determine the degree of resolution in pleural effusions treated with anti-tuberculosis treatment alone without thoracentesis, 62 eligible adult cases [mean age (SD), 46 (17) yrs; 77% male] of tuberculosis pleural effusions treated in two urban-based university teaching hospitals were retrospectively reviewed for changes in effusion size at 2, 6 and 12 months after initiation of treatment. The proportions of patients in whom resolution were complete, partial and unchanged were 64.5%, 27.4% and 8.1%. Effusions with size smaller than three tenth of hemithorax were at three-fold increased likelihood of complete resolution, compared with those with larger effusions [Odds ratio (95% CI): 3.295 (1.033 to 10.514); p=0.04]. Consideration for thoracentesis is therefore still important in certain patients.
Affiliation:
- International Medical University, Malaysia
- International Medical University, Malaysia
- International Medical University, Malaysia
- International Medical University, Malaysia
- International Medical University, Malaysia
- Hospital Tuanku Ja'afar, Malaysia
- International Medical University, Malaysia
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