Online education has become a popular channel for students to pursue their studies not only in developed countries but also in developing countries. This trend is growing impressively but it also brings about some challenges. This study attempts to identify the key challenges faced by students in the online learning of economics. For this purpose, survey data of one hundred and thirty two students from the economics department of Virtual University of Pakistan was collected and then analysed using Statistical Package for the Social Sciences. The main factors which are examined in the study are course contents, learning management system, communication skills, student-teacher communication gap and drawing of graphs. The findings enable us to propose solutions to overcome the problems of online learning of economics, which can be helpful for both universities and students to improve the learning of economics subjects.